glp-1 receptor agonist with dpp-4 inhibitor combination not recommended inhibitors and GLP-1RAs: cardiovascular safety and benefits do not combine dpp-4 inhibitors

Jastreboff et al., NEJM, 2023

Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity (STEP 5)

With this approval, and by launching a generic for Saxenda, we will provide patients in the US the first ever generic GLP-1 product specifically indicated for weight loss, said Ernie Richardsen, senior vice president, Head of US Commercial Generics at Teva

Clin J Am Soc Nephrol 2011;6:141826

Cancer Immunol Immunother (2009) 58(11):172347

If GLP-1 receptor agonists do influence rheumatoid arthritis, the mechanisms would likely involve both direct immunomodulatory effects and indirect benefits through metabolic improvement