is exenatide a glp 1 agonist Frontiers Clinical Focus on GLP-1 Agonists
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Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated

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This interaction triggers multiple beneficial effects, such as enhancing insulin release from the pancreas when glucose levels are high, suppressing glucagon (which raises blood sugar), and signaling the brain to promote fullness

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Tirzepatide was approved in 2022 as Mounjaro for diabetes, and in 2024 as Zepbound for obesity, with exclusivity running until May 2027

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