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Originally developed and positioned as treatments for type 2 diabetes, these agents are now equally associated with weight management, reshaping how clinicians, patients, and pharmacies understand metabolic disease

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The studies involved subjects, rather small numbers in each case, who had diabetes, non-alcoholic fatty liver disease (NAFLD), polycystic ovary syndrome (PCOS), coronary disease or had kidney transplants

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Food and Drug Administrations approval of Eli Lillys once-daily pill orforglipron as a weight loss and obesity treatment this week was the fastest approval of a new medication in decades

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