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Endocrinology 142: 45224528, 2001

There is real evidence for the level effect: Researchers at Cornell and Numerator, using a panel of roughly 150,000 households, found that within six months of a member starting a GLP-1, a household cuts grocery spending by 5.3 percent

Managing gastrointestinal side-effects and preventing treatment discontinuation with GLP-1 therapies GI symptoms are the most common adverse effects of GLP-1 therapies, with nausea, constipation, diarrhea, and vomiting occurring in around 40 % of patients [11,[30], [31], [32]]

Will GLP-1s make people more frail, faster

GLP-1s slow digestion, meaning alcohol stays in your system longer

Their thyroid medication doses may need adjustment as weight changes, but the medications are compatible