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Retatrutide extends this further by incorporating GCGR activation, adding a third metabolic lever that directly increases energy expenditure
Prebiotics feed beneficial gut bacteria , which helps support a balanced microbiome thats associated with greater GLP-1 production

10.2337/db20-0361 10 NewR

1,4,5 Conversely, diets rich in refined carbohydrates and processed foods may suppress this beneficial response
With less food intake, blood sugar levels improve and the body starts to burn stored fat, causing weight loss

Working with a primary care provider or weight loss specialist remains essential to ensure medical appropriateness, rule out contraindications, and establish appropriate dosing
