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Clinical Evidence on Weight Rebound After Treatment Stops The STEP trials, which evaluated semaglutide efficacy, included a follow-up phase where participants stopped medication

Of the weight lost, the reduction in lean body mass (body components excluding fat, such as muscle, bone and water) accounted for only 10.8%

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Persistent Symptoms If you have been on the same dose for over a month and the nausea is not improving, it is time to talk to your provider
