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All of these unanswered questions only add to the urgency of determining who is most likely to benefit from GLP-1s. : Luliia Burmistrova / Getty

In under-resourced parts of Los Angeles, people develop life-altering, preventable diabetes complications related to obesity

The relative risk of symptomatic cholelithiasis was 1.6, 0.9, and 1.4 in liraglutide, dulaglutide, and semaglutide with number needed to harm of 3.14, 16.67, and 5.56, respectively

Although these drugs are FDA-approved to treat specific conditions, such as obesity or type 2 diabetes, research studies for potential additional uses and conditions, beyond obesity and diabetes, are underway.

These medications work by mimicking the action of GLP-1, thereby helping to regulate blood sugar levels and reduce appetite