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Its loss in HD not only increases neuronal susceptibility to damage but also accelerates the neurodegenerative process

Luteolin can also increase the expression of antioxidant enzymes such as heme oxygenase-1 (HO-1) via the nuclear factor erythroid 2related factor 2/ antioxidant responsive element (Nrf-2/ARE) complex activation, as it was observed in in vitro models of PD [44, 57] and H 2 O 2 -induced toxicity in in vitro models [5860]

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Liver ergothioneine accumulation in a guinea pig model of non-alcoholic fatty liver disease

Most of the anabolic and tissue-remodeling effects attributed to IGF-1 signaling run through one or both of these

Aust N Z J Psychiatry 2008;42:467-77