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Cleveland Clinic Thus, the benefits of surgery tend to stick, whereas the benefits of medical therapy once therapy stops or compliance wanes

The study excluded individuals with type 2 diabetes, despite this population frequently presenting with NAFLD, so it remains uncertain whether these safety outcomes would be applicable to them

The underlying biology doesn't change when you stop: hunger hormones return to pre-treatment levels, energy expenditure decreases, and appetite rebounds

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Since then, several GLP1RAs have been approved for the treatment of Type 2 diabetes, and in 2014, the first GLP1RA was approved for the treatment of obesity (body mass index [BMI] 30 kg/m 2 or a BMI 27 kg/m 2 and at least one weightrelated comorbid condition) [45]