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Materials and methods: REDEFINE 1 was a phase 3a, double-blind, placebo (pbo)-controlled, trial in adults with body mass index (BMI) 30 kg/m 2 , or 27 kg/m 2 with 1 obesity-related comorbidity, without diabetes

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Additionally, semaglutide can delay stomach emptying, which may alter how quickly propranolol is absorbed into your bloodstream, affecting its therapeutic window