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The exact mechanisms explaining these findings are not completely understood, but there is some evidence that agonist-induced internalization of the two receptors for GLP-1 and GIP differs markedly
This includes adopting a healthier diet and more exercise

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Additionally, the bidirectional relationship between sleep disturbances and addiction has been increasingly recognized: substance use disrupts sleep architecture, while sleep disorders themselves may predispose to relapse and worsen addiction outcomes [38]

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