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It should also be used cautiously in individuals with a history of pancreatitis, gallbladder disease, or a personal or family history of medullary thyroid carcinoma (MTC) or MEN2

And my patients do really well with this approach

As your weight loss progresses and abdominal fat decreases, you may need to transition to other sites or adjust your technique to maintain proper subcutaneous delivery

2012 Jan;38(1):104-10

Medication injected into lumpy tissue may not absorb consistently, which can lead to unpredictable blood sugar levels, especially for patients who also take insulin along with GLP-1

Approach the patient with obstructive sleep apnea and obesity