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Objective: To evaluate the efficacy and safety of semaglutide combined with metformin in treating type 2 diabetes mellitus (T2DM) patients who are overweight or obese

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Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are highly effective for body weight reduction, there remains a critical unmet need for complementary strategies that drive selective fat loss and sustain long-term weight reduction

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Maintain peristalsis* (the wave-like motion that pushes material through digestion)

Insights from real-world clinical data paint a picture of who responds and who does not to GLP-1s outside of clinical trials.