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Our patients report that the injections are relatively painless and easily tolerated: a thin needle is inserted just below the skin, and we alternate injection sites each week to minimize potential irritation in one area

Treatment typically starts with 0.25 mg once weekly for 4 weeks as an initiation dose (not intended for glycaemic control), then increases to 0.5 mg once weekly

However, real-world evidencewhere availablehas not shown major differences in for example hypoglycemia rate or drug discontinuation (36, 39, 40)

Residents see progress that feels both safe and measurable

CI = confidence interval 1 The intent-to-treat population includes all randomized patients

29 The IWQOL-Lite total score was weakly correlated (magnitude of R between 0.10 and 0.30) with the Marlowe-Crowne social desirability score and SF-36 role emotional score and moderately correlated (magnitude of R between 0.30 and 0.50) with the rest of the measures