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GIP is another incretin hormone released by your gut after meals, and adding this second pathway creates effects that a GLP-1-only drug simply cannot match

Among participants with KDIGO high or veryhighrisk CKD, the mean decline in eGFR by 36 months was 5.72 mL/min/1.73 m with tirzepatide versus 8.90 mL/min/1.73 m with dulaglutide

The FDA specifically advises discontinuing the medication at least two months before attempting conception, prioritizing patient safety until more definitive research emerges

Tirzepatide, the active ingredient in Zepbound and Mounjaro , is a once-weekly injection prescribed to help manage type 2 diabetes, sleep apnea, or support weight loss

Ongoing supervision ensures that tirzepatide treatment remains both safe and effective

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Renehan AG, Tyson M, Egger M, et al