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Description
GLP-1 receptor activation slows gastric emptying, reduces appetite by acting on hypothalamic satiety centres, and stimulates glucose-dependent insulin secretion from pancreatic beta cells
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This safety overview is not exhaustive and does not replace the Patient Drug Education or official prescribing information
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The ADA 2026 Standards of Care now recommend GLP-1 receptor agonists with demonstrated cardiovascular benefit for patients with type 2 diabetes and established ASCVD, multiple cardiovascular risk factors, or chronic kidney disease, and note that combination with SGLT2 inhibitors may provide additive benefit
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