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Furthermore, glucagon enhances hepatic protein and lipid metabolism during a mixed meal

Tirzepatide can influence muscle composition during weight loss, but the risk depends on individual factors including baseline metabolism, protein intake, and exercise patterns

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This is largely driven by rapid gastric emptying and an exaggerated GLP-1 mediated insulin response, particularly after Roux-en-Y gastric bypass (RYGB)

In order to reveal the pathogenic mechanism of digestive diseases, it is necessary to establish a completer and more physiological organoid model

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