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Description
Pembrolizumab and nivolumab which have also been in a category of immune checkpoint inhibitors are approved by FDA as a first line therapy in patients having cisplatin insensitive recurrent or metastatic HNSCC [1921]

STEP 5 examined long-term outcomes over 104 weeks (2 years)

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1996;126(3):756S-760S

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NAD+ and MOTS-C: Mitochondrial Peptide Research, AMPK Signaling & Metabolic Data MOTS-C activates AMPK via NAD+ crosstalk in preclinical models
