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FDA Review Period: 1012 Months Standard review is 10 months

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Dietary counseling and lifestyle modification support, including recommendations for regular physical activity, were provided by a dietitian throughout the study period

doi: 10.1080/0269905031000070170

The most commonly reported adverse effects in Phase 2 trials were gastrointestinal in nature, including: Nausea (the most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and most pronounced during dose escalation, typically improving over time

Karakasis P et al
