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[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Lioutas V-A, Alfaro-Martinez F, Bedoya F, Chung C-C, Pimentel DA, Novak V

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It is a 16-amino acid peptide that activates AMPK, the master metabolic regulator, by inhibiting the folate cycle and accumulating AICAR, a potent endogenous AMPK activator
Mechanism of Action: CJC-1295 mimics natural Growth Hormone-Releasing Hormone (GHRH) in the body, effectively binding to growth hormone-releasing hormone receptors in the anterior pituitary gland

doi: 10.1159/000322008
