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All participants received a standardized lifestyle intervention, which included counseling on a reduced-calorie diet (500 kcal/day deficit) and increased physical activity ( 150 min/week) in addition to study drug or placebo

The GLP-1 can also induce neurite growth, thus achieving the effect of an AD intervention

The data are provided by patients and collected by the UK National Health Service as part of their care and support

Gut barrier function Beyond immune surveillance, epithelial gut barrier function depends on the integrity of the mucin layerwhich limits microbial adhesion and invasionand on tight junctions that maintain epithelial cellcell adhesion and regulate paracellular permeability to antigens and other substrates

Forman, J.L

Diabetes Ther 13(1):175187