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Until those results are in, the recommendation is extrapolated from non-pharmacologic weight-loss literature plus 2024-2025 case reports of GLP-1 patients who lifted and held their lean mass [11]

Some patients lose weight at first, then plateau

This injectable medication can help lower blood sugar levels, promote weight loss, reduce the risk of cardiovascular events, and improve overall well-being

In mouse models of Parkinsons disease induced by either -synuclein preformed fibrils or -synuclein overexpression, treatment with 3 mg/kg NLY01 twice weekly for 5 months protected against neurodegeneration, including -synuclein aggregation and loss of dopaminergic neurons (46)

Known side effects include nausea, vomiting, and abdominal discomfort

The primary outcome was a composite of oral corticosteroid use, initiation of TNF- inhibitors, IBD-related hospitalization, or IBD-related surgery