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He witnessed many patients getting diagnosed with dementia and other neurological conditions because they displayed confusion, anxiety and panic attacks which shared similarities with the symptoms hypoglycaemia

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For example, saxagliptin protected the mitochondrial function in PD rat models by up-regulating complex I and the anti-apoptotic protein Bcl-2 (72), while long-term use of exendin-4 in rodents promoted the function of hippocampal nerves, and improved motor function and behavior (73)

While our analysis identified significant pharmacovigilance signals, we emphasize these findings represent associations rather than established causation

11 It was later determined that higher concentrations were necessary to produce the same effect in vivo