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Whereas GLP-1 acts in the periphery to inhibit glucagon secretion and stimulate insulin release, it also acts in the central nervous system to ...

In clinical trials, GLP-1 RAs were shown to significantly lower blood pressure (BP) in addition to HbA1c and body weight (BW), indicating the possibility as anti-hypertensive medication of type 2 DM individuals

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Glucagon-like peptide-1 (GLP-1) agonists are the latest evolution of drugs that are reshaping the way we treat diabetes, obesity, and other forms of addiction.