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In a transgenic mouse model overexpressing mutant human huntingtin (N171-82Q), once-daily subcutaneous delivery of exendin-4 reduced huntingtin aggregates in the cortex, along with improvements in motor performance and overall survival [93]

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Likewise, daily liraglutide treatment downregulated lung C-C motif chemokine ligand 2 (Ccl2) and IL-6 in mice during influenza infection