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doi: 10.1001/jama.2021.1831 20 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

In one phase 2 trial of people with obesity, some of whom also had type 2 diabetes, participants lost 20.5% of their fat mass while increasin g their lean muscle mass by 3.6% over 48 weeks of treatment

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These may present as localised redness and swelling at the injection site or, less commonly, as widespread urticaria or angioedema
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[DOI] [PubMed] [Google Scholar] 14.Ayesh H., Ayesh S., Niswender K

Tirzepatide adds a second lever, GIP receptor activity
