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doi: 10.3389/fphar.2026.1791206 Received 19 January 2026 Revised 13 April 2026 Accepted 14 April 2026 Published 01 May 2026 Volume 17 - 2026 Edited by Kabirullah Lutfy, Western University of Health Sciences, United States Reviewed by Marsida Kallupi, University of California, San Diego, United States Christina Merritt, University of Texas Medical Branch at Galveston, United States Updates Copyright 2026 Hrickova, Demirci, Amchova and Ruda-Kucerova

Using GLP-1RAs instead of insulin cost US$54,851 and US$29,115 per case of all-cause mortality and hospitalized hypoglycemia prevented, respectively, from the payer perspective, and saved US$19,391 and US$10,293, respectively, from the healthcare sector perspective

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For those who want to experiment with peptides, do so with a clinician tracking weight, hormones, and labs