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Abstract Obesity in reproductive-age women is associated with increased risk of cardiometabolic disease, infertility, and pregnancy-related complications affecting both the mother and fetus

In Klotho knock-out mice, the expression level of Wnt1 is increased and the initially inhibited IRS/Akt pathway is restored (255)

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In patients with type 2 diabetes mellitus (T2DM), supraphysiological doses of GLP1 normalize the endogenous insulin response during a hyperglycaemic clamp

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