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St-Onge MP, Zuraikat FM, Neilson M

The glucose-lowering effect is partly dose-dependent but also reflects the medication's direct action on pancreatic beta cells and glucagon suppression

Wegovy is typically prescribed for adults within a specific BMI range, or with other weight-related health conditions like high blood pressure or type 2 diabetes

It is uncertain whether their effects are similar in non-obese or less-obese populations, or whether benefits extend to other disease subtypes such as hand OA

Niacinamide interactions at the doses used in this formulation are generally limited

Starting with a lower dose and gradually increasing it can help minimize side effects