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Plos One 6 , e25269, (2011)

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GLP-1 contributes to increases in PGC-1 expression by downregulating miR-23a to reduce apoptosis

Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not take GLP-1 medications with the thyroid C-cell tumor boxed warning

Co-agonist strategy Glucose-dependent insulinotropic polypeptide (GIP) and glucagon receptor (GCGR) are currently the primary targets alongside GLP-1R for combined stimulation

Berberine is a plant alkaloid found in barberry root, goldenseal, and Oregon grape
