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IntroductionWith the rise in glucagon-like peptide 1 receptor agonist (GLP-1RA) medication usage for Type 2 diabetes mellitus and weight loss, concerns have ...

Nevertheless, the certainty of the effect size following the GRADE classification was very low. Conclusions In this systematic review and meta-analysis, we found that GLP-1 RAs significantly prolonged gastric emptying T by a mean of 74min, which could have implications for perioperative care

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Orforglipron does not require fasting or other dosing restrictions, which may offer a meaningful practical advantage for patients

doi:10.2337/dc25-SREV

However, they also affect how the digestive system works