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Nearly half of participants in the 6 mg group (49.5%) achieved at least 15% weight reduction , compared to just 2% on placebo

Oral contraceptives, especially those containing estrogen, are known to increase the risk of blood clots

Keeping this in mind, one will not be surprised that spironolactone did not even reduce BP (difference 1

2022 Feb 1 [cited 2025 Feb 17];25(2):468

Altogether, our findings are in line with the results of our earlier study of 30-day dawn to sunset intermittent fasting conducted in healthy subjects 15 and lay the foundation data for a randomized, controlled clinical trial of dawn to sunset intermittent fasting in subjects with metabolic syndrome

When someone has a significant amount of weight to lose, not eating as much initially- no matter the type of food- will cause a calorie deficit