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European Journal of Cancer

Viral replication and proliferation of immunocompetent cells critical to the host response require these essential nutrients, including zinc

Experiments demonstrated that this system could be effectively internalized by inflammatory cells and exhibits high cytotoxicity, while showing low toxicity to normal cells

doi:10.3109/03602532.2011.558093 Oguro T, Hayashi M, Nakajo S, Numazawa S, Yoshida T (1998) The expression of heme oxygenase-1 gene responded to oxidative stress produced by phorone, a glutathione depletor, in the rat liver

Moreover, studies have demonstrated that iron chelator DFO [133] and antioxidant N-acetylcysteine (NAC) [130] could save bone loss induced by iron accumulation

Additionally, most studies on the intestinal barrier protection of TCMs rely heavily on in vitro and animal experiments, with insufficient clinical research data to validate the feasibility and safety of these effects in humans
