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Burke OM, Frerichs VR, Garcia DF, Stone RC, Lev-Tov H, Czarnowicki T, et al

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Mounjaro (tirzepatide) is a dual GIP/GLP-1 receptor agonist that activates both GIP and GLP-1 receptors, whereas traditional GLP-1 receptor agonists such as semaglutide and liraglutide target only the GLP-1 pathway

Gradual weight reduction: Data from the phase 2 randomised controlled trial (Jastreboff et al., New England Journal of Medicine , 2023) showed meaningful reductions in body weight beginning within the first four to eight weeks of treatment, in line with the trial's dose-escalation protocol