can semaglutide affect your heart and Health: Safety Guide for Cardiac Patients GLP-1 Agonists in Cardiovascular Diseases:

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When to Throw Away Your Medication Discard medication if: It has been frozen It was exposed to temperatures above 86F The liquid appears cloudy, discolored, or contains particles It has been used beyond the recommended time If you are unsure, its better to ask before using it

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Researchers emphasized that such incidents remain rare, but expressed concern due to the rapidly growing use of the drugs

If you are scheduled to have surgery, ask about holding medication

Indirect evidence comes from studies showing that GLP-1 agonists improve markers of inflammation (such as C-reactive protein) and reduce metabolic syndrome featuresboth of which correlate with chronic cortisol elevation