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These individuals appear to have a puzzling condition called GLP-1 resistance, where their bodies produce higher levels of the hormone targeted by these drugsbut dont respond to it properly.

In women it takes shape in a Christmas tree distribution and for men it affects the front and temples

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Sandoz CEO says $40$50 monthly pricing could triple patient access to weight-loss drugs

Completion of the trials main phase is expected in September 2025, and the 52-week extension (in which participants and investigators remain blinded to treatment assignment) will continue to October 2026