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doi: 10.1016/j.ejphar.2017.06.029 112

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Supported by multidisciplinary care involving surgeons, endocrinologists, dietitians, and behavioral specialists

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Safety, Side Effects, and What to Expect GLP-1 medications are generally well-tolerated, with the most common side effects being mild nausea, slight appetite reduction (the intended effect), and occasional constipation during the first few weeks

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After five years of follow-up in patients with T2DM, the GLP-1 RAs and SGLT-2 inhibitors groups demonstrated significant reductions in mortality, CHD, HF, AF, stroke, peripheral vascular disease, and CKD, regardless which one of the drugs or its combination were used

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GLP-1a users may have nutrient deficiencies thanks to their lower food intake

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