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Erratum in: Diabetes Care
Unimolecular Polypharmacy for Treatment of Diabetes and Obesity
Thus GLP-1 was shown to regulate a number of diverse functions: reduction in digestive enzyme secretion, slowing of gastric motility, increases in heart rate and blood flow, increased bone remodeling, and suppression of appetite (via hypothalamic and brainstem nuclei)
Matza LS, Stewart KD, Land LF, Patel H, Boye KS (2022) Exit interviews examining the patient experience in clinical trials of tirzepatide for treatment of type 2 diabetes
They mimic the GLP-1 (glucagon-like peptide 1) hormone produced in the gut as a response to eating, which raises insulin production and lowers blood sugar
Why was one study (Lixisanatide) positive and one study (Exenatide) negative for Parkinsons
