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Clinical research on HFrEF patients shows that GLP-1 agonists enhance left ventricular ejection fraction (LVEF) while reducing fibrosis according to preclinical investigations although clinical trial data for liraglutide remains neutral in FIGHT and LIVE [59,60]

Ongoing follow-up with your provider helps manage dosing and side effects

After three years, participants taking GLP-1 drugs experienced a 30% reduction in emergency department visits, a 25% reduction in hospitalizations, a 40% reduction in overdoses, and a 50% reduction in drug-related deaths

and People Magazines year-end cover story about media celebrity Oprah Winfrey, People (December 25, 2023): Oprah Winfrey reveals she uses weight-loss medication as a maintenance tool: Im absolutely done with the shaming (exclusive) ( and 2 This invited perspective article has been part of the recent turns of events, with earlier drafts having circulated since September 2023 to colleagues as well as to journalists investigating Mojsovs role in the discovery of GLP-1