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For semaglutide, the typical starting dose is 0.25 mg weekly, increasing to 0.5 mg, then 1.0 mg, and potentially 2.4 mg over several months

However, these are general guidelines, not automatic qualifiers

Pharmacol Res 210:107517 Lazzaroni E, Ben Nasr M, Loretelli C, Pastore I, Plebani L, Lunati ME et al (2021) Anti-diabetic drugs and weight loss in patients with type 2 diabetes

Schmiedebergs Arch

Starting with lower doses (5 grams or less) and gradually increasing intake can help minimize these effects

These typically subside during the first 48 weeks
