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Primarily, it stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated

Therefore, following the rationale in our previous NMA addressing the risk of neurodegenerative diseases related to GLP-1 receptor agonists and SGLT2 inhibitor use [13], this NMA aims to provide evidence about the comparative risk of hearing loss by GLP-1 receptor agonists and SGLT2 inhibitor use

Proponents claim these patches can suppress appetite, slow gastric emptying, and improve insulin secretioneffects associated with legitimate GLP-1 receptor agonists

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