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To address this issue, beginning in 2025, we implemented an augmented sample drawn from the Forbes Americas Largest Private Companies list, which includes U.S.-based firms with annual revenues of $2 billion or more

Finally, in December 2025 Lilly announced a historic $6 billion plant in Huntsville, Alabama the largest single-site pharma investment in Alabamas history ( [7] )

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.You J., Yang C., Han J., Wang H., Zhang W., Zhang Y., Lu Z., Wang S., Cai R., Li H., et al

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