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Common contributing factors include: Chronic constipation and straining during bowel movements Prolonged sitting on the toilet Diarrhea and frequent bowel movements Increased intra-abdominal pressure Given that Zepbound commonly causes both constipation (in approximately 16-17% of patients) and diarrhea (in about 18-24% of patients), these gastrointestinal effects could theoretically contribute to hemorrhoid development or worsening in susceptible individuals

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doi: 10.1039/d1fo02172a 46 GnzelD.YuA

The combination of protein intake, resistance training, and myHMB provides the best defense against muscle loss during weight reduction