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In June 2023, Merck announced the results of a Phase 2a clinical trial of efinopegdutide , a GLP-1 receptor/glucagon-like peptide-1 receptor dual agonist, for treating NASH

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Antiinflammatory actions of glucagon-like peptide-1based therapies beyond metabolic benefits Text PDF Abstract Therapies based on glucagon-like peptide-1 (GLP-1) reduce rates of cardiovascular and chronic kidney disease in people with type 2 diabetes and/or obesity, with ongoing clinical trials investigating their effects in people with metabolic liver disease, arthritis, and both substance use and neurodegenerative disorders

Weeks 2-3: Appetite Suppression and Portion Control By the second and third weeks, appetite reduction becomes more pronounced and consistent

Insurance providers, including Independence Blue Cross, continue to cover nutrition and behavioral health counseling, incentive programs for fitness and exercise activities and bariatric surgery for people at risk of becoming obese