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Recurrent hypoglycemic episodes (more than one per week) signal that concomitant diabetes medications require dose reduction or discontinuation

If gastrointestinal symptoms become severe, a provider might extend the time between titration steps or recommend a lower final dose

Concurrently, GLP-1 receptor activation stimulates glucose-dependent insulin release from pancreatic beta cells, suppresses inappropriate glucagon secretion, slows gastric emptying, and reduces appetite through central nervous system pathways

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October 2023 Study A recent study investigated how certain diabetes drugs, such as Ozempic and Liraglutide, affect people when used for weight loss, a purpose different from their original design