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John Burns, a board-certified plastic surgeon and the president at Dallas Plastic Surgery Institute

Some practitioners recommend lightly biting the tip of the tongue as a reminder not to swallow

Updated July 2026

Research suggests that berberine may: Improve insulin sensitivity Support healthy glucose metabolism Influence gut microbiota composition Enhance pathways involved in GLP-1 secretion Other ingredients that may support GLP-1 activity include: Prebiotic fibers like inulin Polyphenols from green tea Omega-3 fatty acids These nutrients work by supporting metabolic processes linked to increase GLP-1 naturally, rather than directly mimicking the hormone