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These include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects are broadly consistent with the class effects seen with other GLP-1-based therapies

For researchers tracking side effect differences between the two peptides, dose equivalence is not straightforward

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Tirzepatide is administered through subcutaneous injection once a week and may be taken in the morning, afternoon, or evening

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