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Preclinical studies in animal models have demonstrated that survodutide effectively activates both GLP-1R and GCGR, resulting in reduced body weight, slower gastric emptying, decreased energy intake, increased energy expenditure, and improved glucose tolerance [86]

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Pharmaceutical Manufacturing and Supply Chain Challenges With rising demand for obesity and diabetes drugs, manufacturers face significant challenges: API shortages due to limited global supply

In autism, GLP-1RAs may exert therapeutic effects through anti-inflammatory, antioxidant, and neuroprotective mechanisms

Studies could include pre-clinical or early or late phase human trials

32 proc.)