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But over months and years of treatment, even weekly injections in the same spot accumulate

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Nadeem D., Taye M., Still M.D., et al

One common side effect reported in clinical trials is nausea, which was experienced by 44% of participants

Dose adjustments or dose frequency changes may be needed for hydrochlorothiazide and other medications to avoid serious drug interactions

However, metabolic improvements and lifestyle habits developed during therapy can help minimize rebound weight gain compared to initial weight