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10.1097/MOL.0000000000000750 [DOI] [PubMed] [Google Scholar] 57.Papazafiropoulou AK, Melidonis A, Antonopoulos S

[DOI] [PubMed] [Google Scholar] 3.Peeters A., Barendregt J.J., Willekens F., Mackenbach J.P., Mamun A.A., Bonneux L

4 Also, mean change in body weight was a confirmatory secondary endpoint in these studies

The increased risk for cancer associated with obesity is mediated partly by changes in the immune system

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That said, meaningful metabolic support doesnt require pharmaceutical-level effects
